Rendezetlen fehérjékről (inrtinsically disordered proteins, IDP) szóló szimpóziumot tartottak az MTA TTK földszinti előadótermében 2018. április 11-én, Dosztányi Zsuzsanna szervezésében. Az előadók francia, olasz, argentin, izraeli, belga, dán és magyar intézményekből, valamint az EMBL-ből érkeztek. Köztük szerepelt Silvio Tosatto, az olasz ELIXIR Deputy Head of Node, az Integration and standardization of intrinsically disordered protein data Implementation Study vezetője és Norman Davey, az előbbi Implementation Study társ vezetője is.
A rendezvény rövid programja az alábbiakban olvasható (bővebben a rendezvény honlapján):
Sesssion I - Chair Sonia Longhi |
09.00-09.30 |
Silvio Tosatto |
University of Padova |
Computational resources for intrinsically disordered proteins |
09.30-10.00 |
Cristina Marino Buslje |
Leloir Institute Foundation |
Evolutionary footprints in protein function and structure |
10.00-10.30 |
Dana Reichmann |
Hebrew University of Jerusalem |
The role of protein plasticity in redox-regulated chaperones |
Session II - Chair Peter Tompa |
11.00-11.30 |
Gustavo Parisi |
Universidad Nacional de Quilmes |
Ensembles from ordered and disordered proteins reveal similar structural constraints |
11.30-12.00 |
Sonia Longhi |
Aix-Marseille University |
Partner-Mediated Polymorphism of an Intrinsically Disordered Protein |
12.00-12.30 |
Agnes Tantos |
Institute of Enzymology |
Intrinsically Disordered Regions of Histone Lysine Methyltransferases |
Session III - Chair Gustavo Parisi |
14.00-14.20 |
Matteo Lambrughi |
Danish Cancer Society |
Computational approaches to investigate dynamics of short linear motifs in hub proteins |
14.20-14.40 |
Mainak Guharoy |
Vrije Universiteit Brussels |
Disordered segments regulate protein abundance by encoding a multilayer degron architecture |
14.40-15.10 |
Lucia Chemes |
University of San Martín, Argentina |
Structural and thermodynamic characterization of an intrinsically disordered complex |
15.10-15.40 |
Norman Davey |
University College Dublin |
Discovery and characterisation of human and viral targets of phosphatase PP2A-B56 |
Session IV - Chair Zsuzsanna Dosztányi |
16.10-16.40 |
Bálint Mészáros |
Eötvös Loránd University |
Intrinsically disordered proteins in cancer |
16.40-17.10 |
Peter Tompa |
Vrije Universiteit Brussels |
Structural disorder and phase separation in amyotrophic lateral sclerosis (ALS) |
17.10-17.40 |
Toby Gibson |
EMBL |
Short linear motifs in effector proteins of pathogenic bacteria |